2015年6月23日星期二

CIQ|CAS 486427-17-2|DC Chemicals

CIQ|CAS 486427-17-2|DC Chemicals
CIQ is a positive allosteric modulator selective for NR2C/D containing NMDA receptors (EC50 = 2.7 and 2.8 µM for NR2C and NR2D, respectively).

Product name: CIQ |Cat No. DC8156|Other names: |Cas: 486427-17-2|Molecule Weight: 468|Molecule Formular: C26H26ClNO5| Purity: >98%

A positive allosteric modulator selective for NR2C/D containing NMDA receptors (EC50 = 2.7 and 2.8 µM for NR2C and NR2D, respectively). Increases channel opening frequency of recombinant NR2C/D containing NMDA receptors by two-fold without altering mean open time or EC50 values for glutamate or glycine bindings. No effect on NR2A or NR2B subtypes.

For research and scientific purpose only, not for human use.

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