2015年6月25日星期四

G007-LK|tankyrases 1/2 inhibitor|DC Chemicals

G007-LK|tankyrases 1/2 inhibitor|DC Chemicals

G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor.

Product name: G007-LK |Cat No. DC8222|Other names: G007-LK ,G007-LK,G007-LK |Cas: 1380672-07-0|Molecule Weight: 529.07|Molecule Formular: C25H16ClN7O3S| Purity: >98%

G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor. G007-LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice.

For research and scientific purpose only, not for human use.

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