OAC 1|iPSC reprogramming enhancer|DC Chemicals

OAC 1|iPSC reprogramming enhancer|DC Chemicals

OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming process.

Product name: OAC1 |Cat No. DC8208|Other names: OAC1 |Cas: 300586-90-7|Molecule Weight: 237.26|Molecule Formular: C14H11N3O| Purity: >98%

OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming process.in vitro: OAC1 enhances the formation of Oct4-GFP+ colonies and accelerates the dynamics of reprogramming. OAC1 enhanced reprogramming efficiency through a mechanism that is independent of endogenous Oct4 promoter demethylation. OAC1 enhanced reprogramming efficiency through a mechanism that is distinct from suppressing p53-p21 expression. Luciferase assay revealed that OAC1 had no effect on Topflash activity, although BIO activated the Topflash reporter potently. OAC1 functions through a mechanism that is independent of the Wnt signaling.

For research and scientific purpose only, not for human use.