2015年6月22日星期一

Isavuconazole|Isavuconazole|DC Chemicals

Isavuconazole|Isavuconazole|DC Chemicals
Isavuconazole(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557, exhibits MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.

Product name: Isavuconazole |Cat No. DC8120|Other names: Isavuconazole,Isavuconazole|Cas: 241479-67-4|Molecule Weight: 437.47|Molecule Formular: C22H17F2N5OS| Purity: >98%

Isavuconazole was more active (0.004 mg/liter) than amphotericin B (0.5 mg/liter), itraconazole (0.008 mg/liter), voriconazole (0.03 mg/liter), flucytosine (0.125 mg/liter), and fluconazole (8 mg/liter). There were only two isolates with MICs for isavuconazole that were >0.5 mg/liter: both were C. glabrata isolates, and the MICs were 2 and 4 mg/liter, respectively. Isavuconazole has MIC90 value of  0.016 microg/ml against Cryptococcus neoformans isolates from Cuba.

For research and scientific purpose only, not for human use.

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