GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.
Product name: GNE 477 |Cat No. DC8257|Other names: GNE-477 ,GNE477 |Cas: 1032754-81-6|Molecule Weight: 504.63|Molecule Formular: C21H28N8O3S2| Purity: >98%
GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.GNE-477 is a potent dual PI3K/mTOR inhibitor that displays desirable pharmacokinetic properties in each of three species studied. GNE-477 also exhibited stasis in a PC3 tumor growth inhibition study.
For research and scientific purpose only, not for human use.
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