2015年6月25日星期四

LRRK2-IN-1|LRRK2 inhibitor|DC Chemicals

LRRK2-IN-1|LRRK2 inhibitor|DC Chemicals

LRRK2-IN-1 inhibits both wild-type and G2019S mutant LRRK2 kinase activity with IC50 values of 13 nM and 6 nM , respectively with 0.1 mM ATP in the assay.

Product name: LRRK2-IN-1 |Cat No. DC8237|Other names: LRRK2-IN-1, LRRK2 inhibitor|Cas: 1234480-84-2|Molecule Weight: 570.69|Molecule Formular: C31H38N8O3| Purity: >98%

Potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2). Inhibits both G2019S mutant and wild-type LRRK2 kinase activity (IC50 values are 6 and 13 nM respectively). Causes dephosphorylation, ubiquitination and degradation of LRRK2.

For research and scientific purpose only, not for human use.

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