TAPI-0 | MMP Inhibitor | CAS 143457-40-3|DC Chemicals

TAPI-0 | MMP Inhibitor | CAS 143457-40-3|DC Chemicals
Inhibits TNF-α processing. Also a general matrix metalloprotease and TACE inhibitor.

Product name: TAPI-0 (TNF-α processing inhibitor-0) |Cat No. DC8132|Other names: TAPI-0   TNF Protease Inhibitor 0 ,TAPI0,TAPI 0|Cas: 143457-40-3|Molecule Weight: 456.53|Molecule Formular: C24H32N4O5| Purity: >98%

TAPI-0 is an inhibitor of TACE (IC50 = 50-100 nM) as well as other matrix and membrane metalloproteases.For example, it inhibits meprin (Ki value for human meprin α is 2.2 μM).4 Through these actions TAPI-0 blocks the maturation of cytokines, soluble cytokine receptors, and other proteins that require the action of proteases.

For research and scientific purpose only, not for human use.