IWP-2 supplier|cas 686770-61-6 |DC Chemicals|Supplier|Price|Buy  

IWP-2 supplier|cas 686770-61-6 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: IWP-2 supplier,cas 686770-61-6, Cat No. DC5028, In stock

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Product name: IWP-2, Synonym:　ABC 294640,ABC-294640, Cat No. DC5028, Cas: 686770-61-6, Chemical Name:N/A, Molecular Formula: C22H18N4O2S3, MW: 466.6

IWP-2,cas 686770-61-6, Purity: >98%. Best Price and quality in the market,DC Chemicals,Primary Manufacturer, confirmed by HNMR and HPLC. IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses.

Inhibitor of Wnt processing and secretion. Inactivates Porcn, a membrane-bound O-acyltransferase (MBOAT), and selectively inhibits palmitoylation of Wnt. Blocks Wnt-dependent phosphorylation of Lrp6 receptor and Dvl2, and β-catenin accumulation. Suppresses self-renewal in R1 embryonic stem cells.