MLN-4924 supplier|cas 905579-51-3 |DC Chemicals|Supplier|Price|Buy  

DC Chemials Supply: MLN-4924 supplier,cas 905579-51-3, Cat No. DC5176, In stock

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Product name: MLN-4924, Synonym:　MLN4924; MLN 4924; Nedd8-activating enzyme inhibitor MLN4924., Cat No. DC5176, Cas: 905579-51-3, Chemical Name:((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate, Molecular Formula: C21H25N5O4S, MW: 443.52

MLN-4924,cas 905579-51-3, Purity: >98%. Best Price and quality in the market,DC Chemicals,Primary Manufacturer, confirmed by HNMR and HPLC. MLN4924 is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with IC50 of 4 nM.

MLN4924 is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival. NAE activates Nedd8 (Neural precursor cell expressed, developmentally down-regulated 8), an ubiquitin-like (UBL) protein that modifies cellular targets in a pathway that is parallel to but distinct from the ubiquitin-proteasome pathway (UPP). Functioning in diverse regulatory activities, proteins conjugated to UBLs like Nedd8 typically are not targeted for proteasomal degradation.