CP-547632 |cas 252003-65-9 |DC Chemicals|Supplier|Price|Buy  

CP-547632 |cas 252003-65-9 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: CP-547632 ,cas 252003-65-9, Cat No. DC4132, In stock

Contact: website: www.dcchemicals.com,

sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,

Tel: +86-21-61454686;Fax:+86-21-61642701；

Product name: CP-547632, Synonym:　CP547632, Cat No. DC4132, Cas: 252003-65-9, Chemical Name:N/A, Molecular Formula: C20H24BrF2N5O3S, MW: 532.4

CP-547632 Cas#252003-65-9.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals!  CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively).

Description of CP-547632: CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively). It is selective relative to epidermal growth factor receptor, platelet-derived growth factor , and other related TKs. It also inhibits VEGF-stimulated autophosphorylation of VEGFR-2 in a whole cell assay with an IC50 value of 6 nM. After oral administration of CP-547,632 to mice bearing NIH3T3/H-ras tumors, VEGFR-2 phosphorylation in tumors was inhibited in a dose-dependent fashion (EC50 590 ng/ml). CP-547,632 is a well-tolerated, orally-bioavailable inhibitor presently under clinical investigation for the treatment of human malignancies.

For the detailed information about the solubility of CP-547632 in water, the solubility of CP-547632 in DMSO, the solubility of CP-547632 in PBS buffer, the animal experiment of CP-547632,the in vivo and in vitro test of CP-547632,the cell experiment of CP-547632,the IC50 and EC50 of CP-547632please contact DC Chemicals.