AZD-2281 Olaprib |cas 763113-22-0 |DC Chemicals|Supplier|Price|Buy  

AZD-2281 Olaprib |cas 763113-22-0 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: AZD-2281 Olaprib ,cas 763113-22-0, Cat No. DC4110, In stock

Contact: website: www.dcchemicals.com,

sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,

Tel: +86-21-61454686;Fax:+86-21-61642685；

Product name: AZD-2281 (Olaprib), Synonym:　KU-0059436,AZD 2281 (Olaprib), Cat No. DC4110, Cas: 763113-22-0, Chemical Name:4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one, Molecular Formula: C24H23FN4O3, MW: 434.46

AZD-2281 (Olaprib) Cas#763113-22-0.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1 and PARP2 with IC50 of 5 nM and 1 nM, respectively.

Olaparib (AZD-2281) is a small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Olaparib selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks; PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins and can be activated by single-stranded DNA breaks. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) .

For the detailed information about the solubility of AZD-2281 Olaprib in water, the solubility of AZD-2281 Olaprib in DMSO, the solubility of AZD-2281 Olaprib in PBS buffer, the animal experiment of AZD-2281 Olaprib,the in vivo and in vitro test of AZD-2281 Olaprib,the cell experiment of AZD-2281 Olaprib,the IC50 and EC50 of AZD-2281 Olapribplease contact DC Chemicals.