2014年9月23日星期二

R788 disodium (Fostamatinib) |cas 1025687-58-4 |DC Chemicals  

DC Chemials Supply: R788 disodium(Fostamatinib) ,cas 1025687-58-4, Cat No. DC1013, In stock
Contact:sales@dcchemicals.com, order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-61454686;Fax:+86-21-61642470
Product name: R788 disodium (Fostamatinib), Synonym: R788, Fostamatinib,R-788, Cat No. DC1013, Cas: 1025687-58-4, Chemical Name:2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, sodium salt (1:2), Molecular Formula: C23H24FN6O9P.2Na, MW: 624.42
R788 disodium (Fostamatinib) Cas#1025687-58-4.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! R935788 (Fostamatinib disodium, R788) is a Syk inhibitor with IC50 of 41 nM.
Fostamatinib sodium is an orally available disodium salt of the Syk kinase inhibitor fostamatinib with potential anti-inflammatory and immunomodulating activities. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage. Syk kinase, widely expressed in hematopoietic cells, is a nonreceptor tyrosine kinase that is involved in coupling activated immunoreceptors to signal downstream events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis.For the detailed information about the solubility of R788 disodium (Fostamatinib) in water, the solubility of R788 disodium (Fostamatinib) in DMSO, the solubility of R788 disodium (Fostamatinib) in PBS buffer, the animal experiment of R788 disodium (Fostamatinib),the in vivo and in vitro test of R788 disodium (Fostamatinib),the cell experiment of R788 disodium (Fostamatinib),the IC50 and EC50 of R788 disodium (Fostamatinib)please contact DC Chemicals.

没有评论:

发表评论