YM155 |cas:781661-94-7 |DC Chemicals|Supplier|Price|Buy  

YM155 |cas 781661-94-7 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: YM155 ,cas 781661-94-7, Cat No. DC4119, In stock

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Product name: YM155, Synonym:　YM-155,YM 155, Cat No. DC4119, Cas: 781661-94-7, Chemical Name:1H-Naphth[2,3-d]imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-, bromide (1:1), Molecular Formula: C20H19BrN4O3, MW: 443.29

YM155 Cas#781661-94-7.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! YM155 is a potent IAP (inhibitor of apoptosis proteins) inhibitor for survivin with IC50 of 0.54 nM.

Description of Sepantronium: Sepantronium, also known as YM-155, is a small-molecule proapoptotic agent with potential antineoplastic activity. Survivin inhibitor YM155 selectively inhibits survivin expression in tumor cells, resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and tumor cell apoptosis. Survivin, a member of the inhibitor of apoptosis (IAP) gene family, is expressed during embryonal development and is absent in most normal, terminally differentiated tissues; upregulated in a variety of human cancers, its expression in tumors is associated with a more aggressive phenotype, shorter survival times, and a decreased response to chemotherapy. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

For the detailed information about the solubility of YM155 in water, the solubility of YM155 in DMSO, the solubility of YM155 in PBS buffer, the animal experiment of YM155,the in vivo and in vitro test of YM155,the cell experiment of YM155,the IC50 and EC50 of YM155please contact DC Chemicals.