I-BET151 (GSK1210151A) supplier|cas DC Chemials Supply: I-BET151 (GSK1210151A) supplier,cas 1300031-49-5, Cat No. DC5183, In stock

Contact:sales@dcchemicals.com, order@dcchemicals.com,info@dcchemicals.com,Tel: +86-21-61454686;Fax:+86-21-61642470

Product name: I-BET151 (GSK1210151A), Synonym:　I-BET151; GSK1210151A, Cat No. DC5183, Cas: 1300031-49-5, Chemical Name:7-(3,5-dimethylisoxazol-4-yl)-8-methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one, Molecular Formula: C23H21N5O3, MW: 415.44

I-BET151 (GSK1210151A),cas 1300031-49-5, Purity: >98%. Best Price and quality in the market,DC Chemicals,Primary Manufacturer, confirmed by HNMR and HPLC. I-BET151 (GSK1210151A) is a novel selective BET inhibitor for BRD2, BRD3 and BRD4 with IC50 of 0.5 μM, 0.25 μM, and 0.79 μM, respectively.

I-BET151, also known as  GSK1210151A,  is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin.   I-BET151 (GSK1210151A) shows good oral bioavailability in both the rat and minipig as well as demonstrating efficient suppression of bacterial induced inflammation and sepsis in a murine in vivo endotoxaemia model.