2014年9月20日星期六

Fingolimod hydrochloride |cas 162359-56-0 |DC Chemicals|Supplier|Price|Buy  

Fingolimod hydrochloride |cas 162359-56-0 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Fingolimod hydrochloride ,cas 162359-56-0, Cat No. DC3154, In stock

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-61454686;Fax:+86-21-61642660;

Product name: Fingolimod hydrochloride, Synonym: Gilenia, Cat No. DC3154, Cas: 162359-56-0, Chemical Name:2-(4-octylphenethyl)-2-aminopropane-1,3-diol hydrochloride, Molecular Formula: C19H33NO2.HCl, MW: 343.9

Fingolimod hydrochloride Cas#162359-56-0.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! FTY720 (Fingolimod, Gilenya) is a S1P antagonist with IC50 of 0.033 nM.

Description of Fingolimod: Fingolimod (rINN, codenamed FTY720) is an immunosuppressive drug. It is derived from the myriocin (ISP-1) metabolite of the fungus Isaria sinclairii. It is a structural analogue of sphingosine and gets phosphorylated by sphingosine kinases in the cell (most importantly sphingosine kinase 2). The molecular biology of phospho-fingolimod is thought to lie in its activity at one of the five sphingosine-1-phosphate receptors, S1PR1. It can sequester lymphocytes in lymph nodes, preventing them from moving to the central nervous system for auto-immune responses in multiple sclerosis and was originally proposed as a anti-rejection medication indicated post-transplantation. It has been reported to stimulate the repair process of glial cells and precursor cells after injury. Fingolimod has also been reported to be a cannabinoid receptor antagonist, a cPLA2 inhibitor and a ceramide synthase inhibitor. (source: http://en.wikipedia.org/wiki/Fingolimod).
For the detailed information about the solubility of Fingolimod hydrochloride in water, the solubility of Fingolimod hydrochloride in DMSO, the solubility of Fingolimod hydrochloride in PBS buffer, the animal experiment of Fingolimod hydrochloride,the in vivo and in vitro test of Fingolimod hydrochloride,the cell experiment of Fingolimod hydrochloride,the IC50 and EC50 of Fingolimod hydrochlorideplease contact DC Chemicals.

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