2014年9月23日星期二

Telaprevir (VX-950) |cas 402957-28-2 |DC Chemicals|Supplier|Price|Buy  

DC Chemials Supply: Telaprevir (VX-950) ,cas 402957-28-2, Cat No. DC1008, In stock
Tel: +86-21-61454686;Fax:+86-21-61642470
Product name: Telaprevir (VX-950), Synonym: vx950,Telaprevir,VX 950, Cat No. DC1008, Cas: 402957-28-2, Chemical Name:(1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl)-octahydrocyclopenta[c]pyrrole-1-carboxamide, Molecular Formula: C36H53N7O6, MW: 679.85

Telaprevir (VX-950) Cas#402957-28-2.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.
VX-950 is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus (HCV) NS3-4A serine protease, and it demonstrated excellent antiviral activity both in genotype 1b HCV replicon cells (50% inhibitory concentration [IC50] = 354 nM) and in human fetal hepatocytes infected with genotype 1a HCV-positive patient sera (IC50 = 280 nM). VX-950 forms a covalent but reversible complex with the genotype 1a HCV NS3-4A protease in a slow-on, slow-off process with a steady-state inhibition constant (Ki*) of 7 nM. For the detailed information about the solubility of Telaprevir (VX-950) in water, the solubility of Telaprevir (VX-950) in DMSO, the solubility of Telaprevir (VX-950) in PBS buffer, the animal experiment of Telaprevir (VX-950),the in vivo and in vitro test of Telaprevir (VX-950),the cell experiment of Telaprevir (VX-950),the IC50 and EC50 of Telaprevir (VX-950)please contact DC Chemicals.

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