PHA-739358 danusertib |cas 827318-97-8 |DC Chemicals|Supplier|Price|Buy  

PHA-739358 danusertib |cas 827318-97-8 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply:PHA-739358 danusertib ,cas 827318-97-8, Cat No. DC4125, In stock

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Product name: PHA-739358 (danusertib), Synonym:　N/A, Cat No. DC4125, Cas: 827318-97-8, Chemical Name:(R)-N-(5-(2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide, Molecular Formula: C26H30N6O3, MW: 474.55

PHA-739358 (danusertib) Cas#827318-97-8.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.

Description of Danusertib: Danusertib is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed. This agent may preferentially bind to and inhibit Aurora B kinase. Aurora kinases, a family of serine-threonine kinases, are important regulators of cellular proliferation and division. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) .

For the detailed information about the solubility of PHA-739358 danusertib in water, the solubility of PHA-739358 danusertib in DMSO, the solubility of PHA-739358 danusertib in PBS buffer, the animal experiment of PHA-739358 danusertib,the in vivo and in vitro test of PHA-739358 danusertib,the cell experiment of PHA-739358 danusertib,the IC50 and EC50 of PHA-739358 danusertibplease contact DC Chemicals.