Elesclomol |cas 488832-69-5 |DC Chemicals|Supplier|Price|Buy  

Elesclomol |cas 488832-69-5 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Elesclomol ,cas 488832-69-5, Cat No. DC3156, In stock

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Product name: Elesclomol, Synonym:　STA-4783，STA4783, Cat No. DC3156, Cas: 488832-69-5, Chemical Name:N1',N3'-dimethyl-N1',N3'-di(phenylcarbonothioyl)malonohydrazide, Molecular Formula: C19H20N4O2S2, MW: 400.5

Elesclomol Cas#488832-69-5.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Elesclomol (STA-4783) is a novel potent oxidative stress inducer that illicits pro-apoptosis events among tumor cells..

Elesclomol is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative stress beyond baseline levels elevates ROS beyond sustainable levels, exhausting tumor cell antioxidant capacity, which may result in the induction of the mitochondrial apoptosis pathway. Normal cells are spared because the increase in the level of oxidative stress induced by this agent is below the threshold at which apoptosis is induced. Elesclomol is currently developed by Synta Pharmaceuticals Corp. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

For the detailed information about the solubility of Elesclomol in water, the solubility of Elesclomol in DMSO, the solubility of Elesclomol in PBS buffer, the animal experiment of Elesclomol,the in vivo and in vitro test of Elesclomol,the cell experiment of Elesclomol,the IC50 and EC50 of Elesclomolplease contact DC Chemicals.