Nolatrexed (AG-337) |cas 152946-68-4 |DC Chemicals|Supplier|Price|Buy  

Nolatrexed (AG-337) |cas 152946-68-4 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Nolatrexed (AG-337) ,cas 152946-68-4, Cat No. DC4111, In stock

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Product name: Nolatrexed (AG-337), Synonym:　AG337,Nolatrexed (AG 337), Cat No. DC4111, Cas: 152946-68-4, Chemical Name:N/A, Molecular Formula: C14H14Cl2N4OS, MW: 357.26

Nolatrexed (AG-337) Cas#152946-68-4.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! Nolatrexed (AG-337), inhibits purified recombinant human thymidylate synthase (TS) with a Ki of 11 nM, and displays non-competitive inhibition kinetics. It was further shown to inhibit cell growth in a panel of cell lines of murine and human origin, displaying an IC50 of between 0.39 microM 6.6 microM. TS was suggested as the locus of action of AG-337 by the ability of thymidine to antagonize cell growth inhibition and the direct demonstration of TS inhibition in whole cells using a tritium release assay.

For the detailed information about the solubility of Nolatrexed (AG-337) in water, the solubility of Nolatrexed (AG-337) in DMSO, the solubility of Nolatrexed (AG-337) in PBS buffer, the animal experiment of Nolatrexed (AG-337),the in vivo and in vitro test of Nolatrexed (AG-337),the cell experiment of Nolatrexed (AG-337),the IC50 and EC50 of Nolatrexed (AG-337)please contact DC Chemicals.