Dasatinib (BMS-354825) |cas 302962-49-8 |DC Chemicals|Supplier|Price|Buy 

Dasatinib (BMS-354825) |cas 302962-49-8 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Dasatinib (BMS-354825) ,cas 302962-49-8, Cat No. DC2100, In stock

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Product name: Dasatinib (BMS-354825), Synonym:　Sprycel,BMS354825,Dasatinib (BMS 354825), Cat No. DC2100, Cas: 302962-49-8, Chemical Name:N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide, Molecular Formula: C22H26ClN7O2S, MW: 488.01

Dasatinib (BMS-354825) Cas#302962-49-8.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Dasatinib (BMS-354825, Sprycel) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of ＜1 nM, 0.5 nM and 79 nM, respectively.

Description of Dasatinib: Dasatinib is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib binds to and inhibits the growth-promoting activities of these kinases. Apparently because of its less stringent binding affinity for the BCR-ABL kinase, dasatinib has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations. SRC-family protein-tyrosine kinases interact with variety of cell-surface receptors and participate in intracellular signal transduction pathways; tumorigenic forms can occur through altered regulation or expression of the endogenous protein and by way of virally-encoded kinase genes. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

For the detailed information about the solubility of Dasatinib (BMS-354825) in water, the solubility of Dasatinib (BMS-354825) in DMSO, the solubility of Dasatinib (BMS-354825) in PBS buffer, the animal experiment of Dasatinib (BMS-354825),the in vivo and in vitro test of Dasatinib (BMS-354825),the cell experiment of Dasatinib (BMS-354825),the IC50 and EC50 of Dasatinib (BMS-354825)please contact DC Chemicals.