2014年9月10日星期三

AZD-8055 supplier|cas 1009298-09-2 |DC Chemicals|Supplier|Price|Buy  

AZD-8055 supplier|cas 1009298-09-2 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: AZD-8055 supplier,cas 1009298-09-2, Cat No. DC5084, In stock

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-61454686;Fax:+86-21-61642840;

Product name: AZD-8055, Synonym: AZD-8055; AZD8055; AZD 8055., Cat No. DC5084, Cas: 1009298-09-2, Chemical Name:[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol, Molecular Formula: C25H31N5O4, MW: 465.54

AZD-8055,cas 1009298-09-2, Purity: >98%. Best Price and quality in the market,DC Chemicals,Primary Manufacturer, confirmed by HNMR and HPLC. AZD-8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.

AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression, which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell growth, proliferation, motility, and survival.

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