Birinapant (TL32711) supplier|cas 1260251-31-7 |DC Chemicals|Supplier|Price|Buy  

Birinapant (TL32711) supplier|cas 1260251-31-7 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Birinapant (TL32711) supplier,cas 1260251-31-7, Cat No. DC5023, In stock

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Product name: Birinapant (TL32711), Synonym:　TL-32711; TL32711; TL 32711. Birinapant, Cat No. DC5023, Cas: 1260251-31-7, Chemical Name:(2S,2'S)-N,N'-((2S,2'S)-((3S,3'S,5R,5'R)-5,5'-((6,6'-difluoro-1H,1'H-[2,2'-biindole]-3,3'-diyl)bis(methylene))bis(3-hydroxypyrrolidine-5,1-diyl))bis(1-oxobutane-2,1-diyl))bis(2-(methylamino)propanamide), Molecular Formula: C42H56F2N8O6, MW: 806.94

Birinapant (TL32711),cas 1260251-31-7, Purity: >98%. Best Price and quality in the market,DC Chemicals,Primary Manufacturer, confirmed by HNMR and HPLC. Birinapant (TL32711) is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM, less potent to XIAP.

Birinapant, also known as TL32711,  is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity. As a SMAC mimetic and IAP antagonist, TL32711 binds to and inhibits the activity of IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2. Since IAPs shield cancer cells from the apoptosis process, this agent may restore and promote the induction of apoptosis through apoptotic signaling pathways in cancer cells. IAPs are overexpressed by many cancer cell types and suppress apoptosis by binding and inhibiting active caspases-3, -7 and -9 via their baculoviral lAP repeat (BIR) domains.