2015年6月1日星期一

Pyridostatin(RR 82)|cas 1085412-37-8|supplier|DC Chemicals

Pyridostatin(RR 82)|cas 1085412-37-8|supplier|DC Chemicals
Pyridostatin stabilizes G-quadruplexes, targeting the proto-oncogene SRC and telomeric G-quadruplexes, inducing DNA damage and cell-cycle arrest.

Catlog: DC8091| Product name: Pyridostatin(RR 82)| Cas: 1085412-37-8| Other names: RR82,RR-82| Molecule Formula: C31H32N8O5| MW: 596.63. Purity: >98%

Price: 100mg: 900 USD; 250mg: 1400 USD; 1000mg: 2500 USD

Pyridostatin(RR 82) binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).

For research and scientific purpose only, not for human use.

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