Mps1-IN-2|MPS1-Inhibitor|DC Chemicals

Mps1-IN-2|MPS1-Inhibitor|DC Chemicals
Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM.

Catlog: DC8119| Product name: Mps1-IN-2| Cas: 1228817-38-6| Other names: MPS1-IN2| Molecule Formula: C26H36N6O3| MW: 480.60244. Purity: >98%

Price: 100mg: 850 USD; 250mg: 1500 USD; 1000mg: 2600 USD

Mps1-IN-2 inhibited Mps1 kinase activity with half-maximal inhibitory concentrations (IC50) of 3145 nM when screened at 1 μM ATP (apparent Km for ATP < 1 μM). Both compounds demonstrated greater than 1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk for Mps1-IN-1 and Gak and Plk1 for Mps1-IN-2. The M602Q Mps1 mutant was 5 and 19-fold less sensitive to Mps1-IN-1 and Mps1-IN-2 respectively.

For research and scientific purpose only, not for human use.