WAY181187.HCl（WAY-181,187）|CAS 554403-49-5

WAY181187.HCl（WAY-181,187）|CAS 554403-49-5

WAY-181187 is a potent and selective 5-HT6 receptor agonist. WAY-181187 possesses high affinity binding (2.2 and 4.8 nM, respectively) at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187: EC50=6.6 nM, Emax=93%).


Product Name: WAY181187.HCl（WAY-181,187）|Cat No: DC9668|Cas: 554403-49-5 |Molecule Formular: C15H13ClN4O2S2.HCl|Molecule Weight: 417.33|Other names: WAY181187.HCl（WAY-181,187）


WAY-181187 is a potent and selective 5-HT6 receptor agonist. WAY-181187 possesses high affinity binding (2.2 and 4.8 nM, respectively) at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187: EC50=6.6 nM, Emax=93%). In the rat frontal cortex, acute administration of WAY-181187 (3-30 mg/kg, subcutaneous (s.c.)) significantly increased extracellular GABA concentrations without altering the levels of glutamate or norepinephrine.

For research only, not for human use.