Ingenol |cas 30220-46-3|supplier DC Chemicals
Ingenol is an extremely weak protein kinase C (PKC) activator. Has been found to induce apoptosis and act as an anticancer agent. Ingenol derivatives have received constant and multidisciplinary attention on account of their pleiotropic pattern of biologi
Product Name: Ingenol|Cat No: DC9646|Cas: 30220-46-3|Molecule Formular: 30220-46-3|Molecule Weight: 348.4|Other names: Ingenol
Ingenol is an extremely weak PKC (protein kinase C) activator; has been found to induce apoptosis and act as an anticancer agent.
in vitro: ingenol indeed binds to protein kinase C with a Ki of 30 microM and activates the enzyme. In addition, ingenol was biologically active in 3 separate cell systems, showing effects similar to the phorbol esters on morphological change, cell-cell communication, epidermal growth factor binding, arachidonic acid metabolite release, and ornithine decarboxylase activity.
For research only, not for human use.
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