Nitisinone|cas 104206-65-7|DC Chemicals

Nitisinone|cas 104206-65-7|DC Chemicals

Nitisinone(SC0735) is an inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase.

Target: 4-Hydroxyphenylpyruvate Dioxygenase

Nitisinone is a drug used to slow the effects of hereditary tyrosinemia type 1.

Product Name: Nitisinone|Cat No: DC9561|Cas: 104206-65-7|Molecule Formular: C14H10F3NO5|Molecule Weight: 329.2281|Other names: Nitisinone

Nitisinone(SC0735) is an inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase.
Nitisinone is a drug used to slow the effects of hereditary tyrosinemia type 1. Nitisinone reduced urinary HGA levels from an average of 4.0 +/- 1.8 (SD) g/day to 0.2 +/- 0.2 g/day ( P < .001). Low-dose nitisinone effectively reduced urinary HGA levels in patients with alkaptonuria. Future long-term clinical trials are planned to determine the benefits of nitisinone in preventing joint deterioration and providing pain relief, and its long-term side effects. Nitisinone can prevent the development of liver disease and significantly reduce the risk of developing hepatocellular carcinoma; however, vigorous surveillance for the development of HCC needs to be continued lifelong.

For research only, not for human use!