2016年6月13日星期一

EAI045,EAI-045|EGFR(T790M/C797S) inhibitor

EAI045,EAI-045|EGFR(T790M/C797S) inhibitor

EAI045 is an allosteric inhibitor that targets selected drug-resistant EGFR mutants but spares the wild-type receptor.

Product Name: EAI045|Cat No: DC9665|Cas: N/A|Molecule Formular: C19H16FN3O3S|Molecule Weight: 385.09|Other names: EAI045

EAI045 in combination with cetuximab is effective in mouse models of lung cancer driven by EGFR(L858R/T790M) and by EGFR(L858R/T790M/C797S), a mutant that is resistant to all currently available EGFR TKIs.

For research only, not for human use.

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