iCRT 14|cas 677331-12-3|DC Chemicals

iCRT 14|cas 677331-12-3|DC Chemicals

iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).

IC50 value: 40.3 nM

Target: Wnt inhibitor

Thought to directly influence the interaction between β-catenin and TCF4.

Product Name: iCRT 14|Cat No: DC9639|Cas: 677331-12-3|Molecule Formular: C21H17N3O2S|Molecule Weight: 375.4436|Other names: iCRT 14

iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).
Thought to directly influence the interaction between β-catenin and TCF4. Induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.

For research only, not for human use!