SR3335|cas 293753-05-6|DC Chemicals

SR3335|cas 293753-05-6|DC Chemicals

SR3335 (ML-176) is a selective RORα synthetic ligand, directly binds to RORα, but not other RORs, and functions as a selective partial inverse agonist of RORα in cell-based assays.

Product Name: SR3335|Cat No: DC9615|Cas: 293753-05-6|Molecule Formular: C13H9F6NO3S2|Molecule Weight: 405.3359|Other names: SR3335

SR3335 (ML-176) is a selective RORα synthetic ligand, directly binds to RORα, but not other RORs, and functions as a selective partial inverse agonist of RORα in cell-based assays.
Furthermore, SR3335 suppresses the expression of endogenous RORα target genes in HepG2 involved in hepatic gluconeogenesis including glucose-6-phosphatase and phosphoenolpyruvate carboxykinase. The first selective synthetic RORα inverse agonists may hold utility for suppression of elevated hepatic glucose production in type 2 diabetics.

For research only, not for human use!