SB-674042|cas 483313-22-0|DC Chemicals

SB-674042|cas 483313-22-0|DC Chemicals

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

IC50 value: 3.76 nM (Kd)

Target: OX1 receptor

SB-674042 has  no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors.

Product Name: SB-674042|Cat No: DC9573|Cas: 483313-22-0|Molecule Formular: C24H21FN4O2S|Molecule Weight: 448.5125|Other names: SB-674042

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.
SB-674042 has  no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca2+ mobilization in CHO-DG44 cells stably transfected with the OX1 receptor.

For research only, not for human use!