Jervine|cas 469-59-0|DC Chemicals

Jervine|cas 469-59-0|DC Chemicals

Jervine(11-Ketocyclopamine) is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling; Jervine is an inhibitor of Smo.

IC50 value:

Target: sonic hedgehog

is derived from the Veratrum plant species.

Product Name: Jervine|Cat No: DC9621|Cas: 469-59-0|Molecule Formular: C27H39NO3|Molecule Weight: 425.6035|Other names: Jervine

Jervine(11-Ketocyclopamine) is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling; Jervine is an inhibitor of Smo.
is derived from the Veratrum plant species. It is a close structural analog of cyclopamine which specifically inhibits the hedgehog (Hh) pathway by interaction with the hedgehog signaling protein Smo. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Jervine is an inhibitor of Smo.

For research only, not for human use!