Terutroban|cas 165538-40-9|DC Chemicals
Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.
IC50 value:
Target: TP receptor
in vivo: Terutroban is a selective antagonist of the thromboxane/prostaglandin endoperoxide receptor, in preventing retinal ischaemia in a model of diabetes in rats.
Product Name: Terutroban|Cat No: DC9609|Cas: 165538-40-9|Molecule Formular: C20H22ClNO4S|Molecule Weight: 407.911|Other names: Terutroban
Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.
in vivo: Terutroban is a selective antagonist of the thromboxane/prostaglandin endoperoxide receptor, in preventing retinal ischaemia in a model of diabetes in rats. Terutroban significantly protect retinal vascularity from ischaemia in experimental diabetes, and this result could be attributed not only to its antiplatelet/antithrombotic activities but also to its vascular properties.Terutroban has antiplatelet properties. In addition, Terutroban has shown to improve flow-mediated dilatation of the brachial artery after a single administration in patients with coronary artery disease.Terutroban is a potent antithrombotic agent and also possesses antiatherosclerotic and antivasoconstrictor properties.
For research only, not for human use!
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