U0126|cas 109511-58-2| DC Chem|Supplier|Price|Buy
U0126|cas 109511-58-2| DC Chem|Supplier|Price|Buy
DC Chemicals Supply: U0126|cas 109511-58-2,Purity: >98% ,Cat No. DC7243, In stock.
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U0126|cas 109511-58-2 ,Synonym: U0126-EtOH; U 0126; U-0126 ,Chemical name: 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene ,Molecular Formula: C18H16N6S2 ,MW:380.48
U0126, cas 109511-58-2,Purity: >98%, Best Price and quality from DC Chemicals. U0126-EtOH(U-0126) is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD098059.
Potent and selective non-competitive inhibitor of MAP kinase kinase. Inhibits MEK-1 and MEK-2 (IC50values of 0.07 and 0.06 μM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4. Centrally active following systemic administration in vivo. Also available as part of the MAPK Cascade Inhibitor Tocriset? and MAPK Inhibitor Tocriset?. Negative control U0124 (Cat. No. 1868) also available.
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