2014年8月30日星期六

Ixazomib (MLN-9708) supplier|cas 1201902-80-8 |DC Chemicals|Supplier|Price|Buy  

Ixazomib (MLN-9708) supplier|cas 1201902-80-8 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Ixazomib (MLN-9708) supplier,cas 1201902-80-8, Cat No. DC5089, In stock

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-61454686;Fax:+86-21-61642845;

Product name: Ixazomib (MLN-9708), Synonym: Ixazomib; MLN9708, Cat No. DC5089, Cas: 1201902-80-8, Chemical Name:4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid, Molecular Formula: C20H23BCl2N2O9, MW: 517.12

Ixazomib (MLN-9708),cas 1201902-80-8, Purity: >98%. Best Price and quality in the market,DC Chemicals,Primary Manufacturer, confirmed by HNMR and HPLC. MLN9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.

ixazomib is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. Ixazomib inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome, which results in an accumulation of unwanted or misfolded proteins; disruption of various cell signaling pathways may follow, resulting in the induction of apoptosis. Compared to first generation PIs, second generation PIs may have an improved pharmacokinetic profile with increased potency and less toxicity. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquinated.

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