AR-A014418|cas 487021-52-3| DC Chem|Supplier|Price|Buy  

AR-A014418|cas 487021-52-3| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: AR-A014418|cas 487021-52-3,Purity: >98% ,Cat No. DC7004, In stock.

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AR-A014418|cas 487021-52-3 ,Synonym: AR-AO 14418; AR 0133418; AR 014418; GSK 3β inhibitor  ,Chemical name: 1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea ,Molecular Formula: C12H12N4O4S  ,MW:308.31308

AR-A014418, cas 487021-52-3,Purity: >98%, Best Price and quality from DC Chemicals. AR-A014418 is a selective and effective GSK3β inhibitor with an IC 50 value of 104 +/- 27 nM; no significant inhibition on 26 other kinases. 

Cell-permeable. A selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC?? = 104 nM). Inhibition is competitive with respect to ATP (Ki = 38nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC?? values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices.