GSK525762 (I-BET-762) supplier|cas 1260907-17-2 |DC Chemicals|Supplier|Price|Buy  

GSK525762 (I-BET-762) supplier|cas 1260907-17-2 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: GSK525762 (I-BET-762) supplier,cas 1260907-17-2, Cat No. DC5147, In stock

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Product name: GSK525762 (I-BET-762), Synonym:　GSK525762; GSK525762; GSK525762. I-BET-762., Cat No. DC5147, Cas: 1260907-17-2, Chemical Name:N/A, Molecular Formula: C22H22ClN5O2, MW: 423.9

GSK525762 (I-BET-762),cas 1260907-17-2, Purity: >98%. Best Price and quality in the market,DC Chemicals,Primary Manufacturer, confirmed by HNMR and HPLC. GSK 525762A is a potent small molecule inhibitors that disrupt the function of the BET family of bromodomains (Brd2, Brd3, and Brd4).

GSK525762 is a small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins with potential antineoplastic activity. Upon administration, the BET inhibitor GSK525762 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth. Characterized by a tandem repeat of bromodomain at the N-terminus, BET proteins, comprising of BRD2, BRD3, BRD4 and BRDT, are transcriptional regulators that play an important role during development and cellular growth.