S1RA|cas 878141-96-9| DC Chem|Supplier|Price|Buy  

S1RA|cas 878141-96-9| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: S1RA|cas 878141-96-9,Purity: >98% ,Cat No. DC7274, In stock.

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S1RA|cas 878141-96-9 ,Synonym: E-52862; E52862; E 52862  ,Chemical name:  ,Molecular Formula: C20H23N3O2 ,MW:337.42

S1RA, cas 878141-96-9,Purity: >98%, Best Price and quality from DC Chemicals. S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM).

S1RA, E-52862, or 4-(2-((5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yl)oxy)ethyl)morpholine is a selective sigma-1 receptor antagonist, with a reported binding affinity of Ki = 17.0 ± 7.0 nM, selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels.[1][2] In preclinical studies, S1RA has demonstrated efficacy in relieving neuropathic pain and pain in other sensitizing conditions, associated with an improvement of the emotional negative state.