2014年8月10日星期日

Salidroside|cas 10338-51-9| DC Chem|Supplier|Price|Buy 

Salidroside|cas 10338-51-9| DC Chem|Supplier|Price|Buy
DC Chemicals Supply: Salidroside|cas 10338-51-9,Purity: >98% ,Cat No. DC7275, In stock.

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Salidroside|cas 10338-51-9 ,Synonym:  ,Chemical name:  ,Molecular Formula: C14H20O7 ,MW:300.3

Salidroside, cas 10338-51-9,Purity: >98%, Best Price and quality from DC Chemicals. Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties.

Salidroside inhibits the growth of various human cancer cell lines in concentration- and time-dependent manners, and the sensitivity to salidroside is different in those cancer cell lines. Salidroside could cause G1-phase or G2-phase arrest in different cancer cell lines, meanwhile, salidroside resultes in a decrease of CDK4, cyclin D1, cyclin B1 and Cdc2, and upregulates the levels of p27(Kip1) and p21(Cip1). [1] Salidroside also alleviates cell viability loss and apoptotic cell death induced by H(2)O(2) stimulation in cultured NGF-differentiated PC12 cells by activating ERK1/2 pathway and inhibiting caspase-3 activation. [2] Salidroside activates the PI3K/Akt pathway resulting in protective effects against MPP(+)-induced apoptosis in PC12 cells, which may be used in the treatment of Parkinson's disease (PD). Salidroside (20, 50 and 100 mg/kg) protects liver tissue from the oxidative stress elicited by D-galactosamine and lipopolysaccharide.

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