TAK-960|cas 1137868-52-0| DC Chem|Supplier|Price|Buy 

TAK-960|cas 1137868-52-0| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: TAK-960|cas 1137868-52-0,Purity: >98% ,Cat No. DC7309, In stock.

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TAK-960|cas 1137868-52-0 ,Synonym:  ,Chemical name: 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-8H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide ,Molecular Formula: C27H34F3N7O3 ,MW:561.6

TAK-960, cas 1137868-52-0,Purity: >98%, Best Price and quality from DC Chemicals. TAK-960 has shown activity in several tumor cell lines including those that express multi-drug resistant protein 1 (MDR1). Consistent with PLK1 inhibition, TAK-960 treatment gives rise to accumulation of G2/M cells, aberrant "polo" mitosis morphology, and increases phosphorylation of histone H3 (pHH3). TAK-960 inhibits proliferation of multiple cancer cell lines, with mean EC50 values ranging from 8.4 to 46.9 nM.

TAK-960 has shown activity in several tumor cell lines including those that express multi-drug resistant protein 1 (MDR1). Consistent with PLK1 inhibition, TAK-960 treatment gives rise to accumulation of G2/M cells, aberrant "polo" mitosis morphology, and increases phosphorylation of histone H3 (pHH3). TAK-960 inhibits proliferation of multiple cancer cell lines, with mean EC50 values ranging from 8.4 to 46.9 nM.