SCH 900776|cas 891494-64-7| DC Chem|Supplier|Price|Buy  

SCH 900776|cas 891494-64-7| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: SCH 900776|cas 891494-64-7,Purity: >98% ,Cat No. DC7282, In stock.

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SCH 900776|cas 891494-64-7 ,Synonym: SCH 900776; SCH-900776  ,Chemical name: 6-bromo-3-(1-methylpyrazol-4-yl)-5-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine ,Molecular Formula: C15H18BrN7  ,MW:376.25432

SCH 900776, cas 891494-64-7,Purity: >98%, Best Price and quality from DC Chemicals. SCH900776 is a potent, selective and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50 = 3 nM), highly selective against Chk2 (IC50 = 1500 nM) and cyclin-dependent kinase CDK2 (IC50 = 160 nM).

SCH 900776 is a potent and functionally selective inhibitor targeting cell cycle checkpoint kinase 1 (Chk1) (IC50 = 3 nM), Cdk2 (IC50 = 0.16 ?M), and Chk2 (IC50 = 1.5 ?M). Chk1 is an essential serine/threonine kinase which responds to DNA damage and stalls DNA replication, Chk1 is also essential for maintenance of replication fork viability during exposure to DNA antimetabolites. SCH 900776 is a weak inhibitor of CDK2.