PU-H71|cas 873436-91-0| DC Chem|Supplier|Price|Buy  

PU-H71|cas 873436-91-0| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: PU-H71|cas 873436-91-0,Purity: >98% ,Cat No. DC7248, In stock.

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PU-H71|cas 873436-91-0 ,Synonym: PU-H 71; PU H71  ,Chemical name: 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine ,Molecular Formula: C18H21IN6O2S ,MW: 512.36781

PU-H71, cas 873436-91-0,Purity: >98%, Best Price and quality from DC Chemicals. PU-H71 is a potent Hsp90 inhibitor with IC50 of 50 nM. 

Potent inhibitor of heat shock protein 90 (Hsp90) (IC50 = 51 nM in MDA-MB-468 cells). Also inhibits cell growth in a range of breast cancer cell lines (IC50 values are 17, 31, 65, 87 and 140 nM for SKBr3, MCF-7, MDA-MB-468, HCC-1806 and MDA-MB-231 cells respectively). Shown to inhibit cell proliferation and induce apoptosis in triple-negative breast cancer (TNBC) cells.