FR 180204|cas 865362-74-9| DC Chem|Supplier|Price|Buy  

FR 180204|cas 865362-74-9| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: FR 180204|cas 865362-74-9,Purity: >98% ,Cat No. DC7285, In stock.

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FR 180204|cas 865362-74-9 ,Synonym:  ,Chemical name: 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine ,Molecular Formula: C18H13N7 ,MW:327.34

FR 180204, cas 865362-74-9,Purity: >98%, Best Price and quality from DC Chemicals. Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30 μM. Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1 μM).

Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30 μM. Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1 μM).