PluriSln 1(NSC 14613) |cas 91396-88-2| DC Chem|Supplier|Price|Buy  

PluriSln 1(NSC 14613) |cas 91396-88-2| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: PluriSln 1(NSC 14613) |cas 91396-88-2,Purity: >98% ,Cat No. DC7239, In stock.

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PluriSln 1(NSC 14613) |cas 91396-88-2 ,Synonym: NSC 14613  ,Chemical name: 4-Pyridinecarboxylicacid,2-phenylhydrazide ,Molecular Formula: C12H11N3O ,MW:213.24

PluriSln 1(NSC 14613) , cas 91396-88-2,Purity: >98%, Best Price and quality from DC Chemicals. PluriSln 1(NSC 14613) is an inhibitor of stearoyl-coA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs.

PluriSIns #1 has a robust, rapid, and selective cytotoxic effect toward hPSCs. Apoptosis is the central cell death mechanism activated by PluriSIn #1. PluriSIn #1 leads to ER stress in hPSCs. PluriSIn #1 (20 μM) induces ~30% decrease in protein synthesis in hPSCs. PluriSIn #1 exposure induces a ~65% decrease in stearoyl-coA desaturase (SCD1) activity in hPSCs. PluriSIn #1 (20 μM) prevents teratoma gormation from undifferentiated hPSCs PluriSIns also inhibits mPSCs and hinders mouse embryonic development. [1]