2014年8月10日星期日

GSK-650394|cas 890842-28-1| DC Chem|Supplier|Price|Buy  

GSK-650394|cas 890842-28-1| DC Chem|Supplier|Price|Buy
DC Chemicals Supply: GSK-650394|cas 890842-28-1,Purity: >98% ,Cat No. DC7291, In stock.

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GSK-650394|cas 890842-28-1 ,Synonym: GSK650394GSK-650394  ,Chemical name: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoicacid ,Molecular Formula: C25H22N2O2 ,MW: 382.45438

GSK-650394, cas 890842-28-1,Purity: >98%, Best Price and quality from DC Chemicals. GSK650394 is a novel SGK inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2 in the SPA assay respectively. 

Serum- and glucocorticoid-regulated kinase 1 (SGK1) inhibitor (IC50 values are 62 and 103 nM for SGK1 and SGK2 respectively). Displays >30-fold selectivity over Akt and other related kinases. Inhibits androgen-stimulated growth of LNCaP cells, a human prostate carcinoma cell line (IC50 ~ 1 μM).

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