AZD9291|cas 1421373-65-0| DC Chem|Supplier|Price|Buy  

AZD9291|cas 1421373-65-0| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: AZD9291|cas 1421373-65-0,Purity: >98% ,Cat No. DC7006, In stock.

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AZD9291|cas 1421373-65-0 ,Synonym: EGFR inhibitor; AZD9291; AZD 9291  ,Chemical name:  ,Molecular Formula: C28H33N7O2 ,MW:499.61

AZD9291, cas 1421373-65-0,Purity: >98%, Best Price and quality from DC Chemicals. AZD-9291 is a potent and selective mutated forms EGFR inhibitor(Exon 19 deletion EGFR IC50=12.92 nM, L858R/T790M EGFR IC50= 11.44 nM, wild type EGFR IC50= 493.8 nM). 

AZD-9291 is a potent and selective mutated forms EGFR inhibitor(Exon 19 deletion EGFR IC50=12.92 nM, L858R/T790M EGFR IC50= 11.44 nM, wild type EGFR IC50= 493.8 nM). IC50 value: 12.92 nM(Exon 19 deletion EGFR); 11.44 nM(L858R/T790M EGFR) [1] Target: L858R/T790M EGFR; Exon 19 deletion EGFR AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. It inhibits both activating and resistant EGFR mutations while sparing the normal form of EGFR that is present in normal skin and gut cells, thereby reducing the side effects encountered with currently available medicines.