2016年12月28日星期三

AZD8835|cas 1620576-64-8|DC Chemicals

AZD8835|cas 1620576-64-8|DC Chemicals

AZD8835 ia a novel mixed inhibitor of PI3Kα and PI3Kδ with IC50 of 6.2 nM and 5.7 nM, respectively, also with selectivity against PI3Kβ (IC50=431 nM) and PI3Kγ (IC50=90 nM).

Product Name: AZD8835|Cat No: DC9879|cas: 1620576-64-8|Other Names:

AZD8835 ia a novel mixed inhibitor of PI3Kα and PI3Kδ with IC50 of 6.2 nM and 5.7 nM, respectively, also with selectivity against PI3Kβ (IC50=431 nM) and PI3Kγ (IC50=90 nM).

For the research and scientific use only, not for human use!

ATI-2341|cas 1337878-62-2|DC Chemicals

ATI-2341|cas 1337878-62-2|DC Chemicals

ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.

Product Name: ATI-2341|Cat No: DC9878|cas: 1337878-62-2|Other Names:

ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.

For the research and scientific use only, not for human use!

Lauric Acid|cas 143-07-7|DC Chemicals

Lauric Acid|cas 143-07-7|DC Chemicals

Lauric Acid is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.

Product Name: Lauric Acid|Cat No: DC9877|cas: 143-07-7|Other Names:

Lauric Acid is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.

For the research and scientific use only, not for human use!

Pantoprazole|cas 102625-70-7|DC Chemicals

Pantoprazole|cas 102625-70-7|DC Chemicals

Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

Product Name: Pantoprazole|Cat No: DC9876|cas: 102625-70-7|Other Names:

Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

For the research and scientific use only, not for human use!

Ciliobrevin A(HPI4)|ciliogenesis/Hedgehog pathway inhibitor-4

Ciliobrevin A(HPI4)|ciliogenesis/Hedgehog pathway inhibitor-4

Ciliobrevin A(HPI-4) is a Hedgehog pathway inhibitor and ciliogenesis inhibitor.

Product Name: Ciliobrevin A(HPI4)|Cat No: DC9875|cas: 302803-72-1|Other Names: HPI-4,HPI 4

HPI-4 is a Hedgehog pathway inhibitor and ciliogenesis inhibitor. The Hedgehog (HH) signaling pathway is targeted for anti-cancer therapeutics and HPI-4 blocks Sonic hedgehog (Shh)-induced hedgehog pathway activation (IC50 = 7 μM) downstream of Smo. It also inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.

For the research and scientific use only, not for human use!

ML-348(ML348)|LYPLA1 inhibitor

ML-348(ML348)|LYPLA1 inhibitor

ML 348(ML348) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).

Product Name: ML-348(ML348)|Cat No: DC9874|cas: 899713-86-1|Other Names: ML 348

ML 348(ML348) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).Exhibits 14-fold selectivity for LYPLA1 over LYPLA2. Also selective over a panel of ~30 other serine hydrolases.

For the research and scientific use only, not for human use!

Selonsertib|GS-4997|GS4997|ASK1 inhibitor

Selonsertib|GS-4997|GS4997|ASK1 inhibitor

Selonsertib(GS-4997)is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

Product Name: Selonsertib(GS-4997)|Cat No: DC9873|cas: 1448428-04-3|Other Names: GS4997,GS 4997

Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby preventing its phosphorylation and activation. GS-4997 prevents the production of inflammatory cytokines, down-regulates the expression of genes involved in fibrosis, suppresses excessive apoptosis and inhibits cellular proliferation.

For the research and scientific use only, not for human use!