SSR-240612|SSR240612|cas 464930-42-5

SSR-240612|SSR240612|cas 464930-42-5

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Product Name: SSR-240612 HCl |CAS: 464930-42-5|Cat No: DC10799|Other Names: SSR-240612; SSR240612; SSR 240612

SSR-240612 is a bradykinin B1 receptor antagonist potentially for the treatment of chronic pain.

SSR240612 blocked tactile and cold allodynia at 3h (ID50=5.5and 7.1mg/kg,respectively) in glucose‐fed rats but had no effect in control rats. The antagonist (10mg/kg) had no effect on plasma glucose and insulin, insulin resistance (HOMA index) and aortic superoxide anion production in glucose-fed rats.