2018年5月18日星期五

LY2510924|LY-2510924|CXCR4 inhibitor

LY2510924|LY-2510924|CXCR4 inhibitor

DC Chemicals, Website:www.dcchemicals.com

Product Name: LY2510924|CAS: 1088715-84-7 |Cat No: DC10782|Other Names: LY2510924; LY-2510924; LY 2510924

LY2510924 is an inhibitor of CXC chemokine receptor 4 (CXCR4), with potential antineoplastic activity.

LY2510924 is an inhibitor of CXC chemokine receptor 4 (CXCR4), with potential antineoplastic activity. Upon subcutaneous administration, CXCR4 inhibitor LY2510924 binds to the chemokine receptor CXCR4, thereby preventing CXCR4 binding to its ligand, stromal derived factor-1 (SDF-1), and subsequent receptor activation. This may result in decreased tumor cell proliferation and migration. CXCR4, a chemokine receptor belonging to the G protein-coupled receptor (GPCR) gene family, plays an important role in chemotaxis and angiogenesis and is upregulated in several tumor cell types.

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