ALB-127158(a)|ALB-127158 A|cas 1173154-32-9

ALB-127158(a)|ALB-127158 A|cas 1173154-32-9

DC Chemicals, Website:www.dcchemicals.com

Product Name: ALB-127158 A|CAS: 1173154-32-9|Cat No: DC10780|Other Names: ALB-127158A; ALB 127158A; ALB127158A; ALB-127158(a); ALB127158(a); ALB 127158(a); ALB-127158; ALB 127158; ALB127158,1173154-32-9

ALB-127158A, also known as ALB-127158(a), is a MCH1 antagonist for the treatment of obesity.

reclinical studies demonstrated that the compound produced significant weight loss in rodents. ALB-127158(a) may be a potential treatment for IBD. This example demonstrates how using data from the preclinical studies is possible to build decision points into an early clinical development plan that will allow early assessment of potential efficacy and allow timely go/no go decisions.The study, comprising the single ascending dose (SAD) and 14-day multiple ascending dose (MAD) arms, included standard safety assessments, ECG monitoring, and PK measurements. ALB-127158(a) was well tolerated in both the SAD and the MAD. Reported events were mild and showed little dose relationship.